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Furosemide or nitrates for acute heart failure

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Abstract. The purpose of this article is to review the clinical efficacy and safety of nitrates in acute heart failure (AHF) by examining various trials on nitrates in AHF. . Patients were randomised to receive either low-dose IV furosemide (40 mg) and high-dose IV isosorbide dinitrate (3, mcg) every 5 minutes, or 1 mg/hour of  ‎How Nitrate Works · ‎Do Nitrates Have any Effect · ‎Are High-dose Nitrates. MeSH terms. Acute Disease; Administration, Sublingual; Diuretics/therapeutic use*; Furosemide/therapeutic use*; Heart Failure/drug therapy*; Hemodynamics/drug effects; Humans; Infusions, Intravenous; Nitrates/therapeutic use*; Vasodilator Agents/therapeutic use*.

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Intravenous nitrates are widely used in the management of acute heart failure syndrome (AHFS), yet with lack of robust evidence to support their use. In comparison with furosemide, ISDN showed no effect on pulmonary artery pressures, suggesting no real major haemodynamic differences between the two agents when. WAIKOLOA, HAWAII - High-dose rather than low-dose nitrates should be given as first-line therapy to patients with acute heart failure. In one such study, a group of 56 patients using a combination of high-dose nitrates and low-dose furosemide were compared with a group of 54 patients using high-dose furosemide and.

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